Simply as Novo Nordisk confirmed indicators of a restoration, one other chilly bathe hit buyers as the drugmaker shock pre-released its 2026 forecast late Tuesday, sending shares tumbling.
Novo Nordisk’s inventory plummeted 18% in Copenhagen early Wednesday, monitoring losses seen in its American depositary shares on Tuesday and greater than wiping out features seen up to now this 12 months.
“Folks ought to anticipate that it goes down before it comes again up,” CEO Mike Doustdar advised CNBC’s “Early Version Europe” on Wednesday, highlighting the headwinds of considerably decrease U.S. pricing on its best-selling weight reduction drug Wegovy.
“We didn’t go into the small print of the magnitude of that – with the steerage we’re giving that vary.”

It follows Novo’s steerage for 2026 gross sales and working revenue each declining between 5% and 13%, far worse than analysts had anticipated.
Barclays analysts mentioned some would possibly counsel the information to be a “kitchen sink” that will be overwhelmed, “although we observe the identical was mentioned final 12 months, and this proved to not be the case.”
In July final 12 months, Novo slashed steerage for 2025, citing a difficult U.S. market, resulting in shares to crash 23% on the day.
A U-shaped restoration?
“We’re creating affordability for the sufferers, hundreds of thousands of sufferers which can be proper now in want of GLP-1 merchandise, however merely couldn’t afford it. To try this brief time period, you must take a headwind. However after all, there is a very lengthy tailwind for years to return,” Doustdar advised CNBC.
The corporate has flagged challenges round pricing in its largest market, the U.S., on account of each competitors from compounding pharmacies that promote cheaper knockoff variations of semaglutide – the energetic ingredient in Wegovy and Ozempic – as nicely as from chief rival U.S.-based Eli Lilly.
However optimism grew early this 12 months as the launch of the Wegovy capsule within the U.S. went better than even Novo had anticipated. “We knew it’s going to be the very best when it comes to efficacy of 16.6% we had anticipated it to do nicely, however we didn’t assume that after 4 weeks of introduction, we will have 170,000 folks on the capsule,” mentioned Doustdar.
“Irrespective of how nicely it does within the preliminary interval, the value hit on the present enterprise trumps, principally, the nice capsule launch that we have had.”
Whereas Novo has labored to handle expectations going into its full-year outcomes, the place it additionally introduced steerage for the 12 months to return, the market didn’t see this coming.
“The query turns into if the restoration from right here, [will be] a Nike swoosh or U-shaped restoration,” famous HSBC’s Rajesh Kumar.
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