At 4:40 a.m. on Might 4, 2026, a 40-year-old man got here to Khanna Sub-divisional Hospital’s emergency division with sweating and chest ache. Inside minutes, the employees nurse and Emergency Medical Officer (EMO) had checked his heart fee, blood strain, blood sugar and extra importantly, carried out an electrocardiogram (ECG).
The ECG outcome was despatched on WhatsApp to the hospital’s medication guide, Shiney Aggarwal, who identified it as an ST-elevated myocardial infarction (STEMI) case and requested the EMO to administer the injection tenecteplase.

Dr Shiney Aggarwal with the emergency employees at SDH Khanna.
| Photograph Credit score:
Swagata Yadavar
STEMI is a extreme, life-threatening heart attack with vital coronary artery blockage. The injection tenecteplase is used for thrombolysis or dissolving the clot, by performing on the protein holding it collectively, restoring blood provide to the heart.
The affected person acquired the injection inside half an hour of his ECG outcomes and quickly felt reduction. Out of hazard, he was referred to Authorities Medical Faculty Patiala (54 km) for additional investigations and remedy.
This case marked the one hundredth thrombolysis case of the hospital and the very best recorded by any centre in Punjab. A couple of years in the past, any chest ache affected person in secondary well being centres equivalent to sub-divisional and district hospitals would have been instantly referred to medical faculties for additional remedy.
Had that occurred on this case, the 40-70 minutes that the affected person misplaced in transportation and additional prognosis would have meant irreversible harm to his heart muscle tissues and their means to work sooner or later.

ICMR mission to a state-wide mission
Since July 2025, the Punjab authorities has carried out Mission AMRIT (Acute Myocardial Reperfusion in Time) throughout the State the place employees members of sub-divisional hospitals and district hospitals (spokes) are outfitted with medicine, gear and training to conduct thrombolysis underneath the steering of a heart specialist or a specialist within the medical faculties (hubs).
Until date, about 34,000 folks with chest ache have been registered within the spokes out of which 1900 had been recognized as STEMI circumstances, 900 have acquired thrombolysis and a lot of them acquired angiography and angioplasty within the hubs. The initiative has expanded the work achieved by the Indian Council of Medical Analysis (ICMR)’s STEMI ACT mission carried out in a single district of seven states and one union territory between 2020-2024.
“In our examine, at the least round 8000 sufferers have been thrombolised and we’re in a position to virtually triple the thrombolysis fee the place nothing was taking place earlier than,” mentioned S. Ramakrishnan, guide heart specialist, AIIMS and Nationwide Principal Investigator, ICMR ACT mission, that concluded in December 2024. He mentioned the present focus of the examine is on growing entry to thrombolysis and not growing the speed of angioplasties due to paucity of cath labs and the excessive price of the process.
In accordance to Hitinder Kaur, Director, Well being Providers of Division of Well being and Household Welfare, Punjab, STEMI sufferers are receiving Rs 35,000 price of remedy freed from price inside minutes, offering well timed remedy. This work continued even through the 2025 floods and in difficult (Pakistan bordering) districts together with Tarn Taran and Ferozepur throughout Operation Sindoor.
The mannequin operates merely – the spokes are outfitted with ECG machines, defibrillators, heart screens and fridges to retailer tenecteplase. The employees is skilled to conduct ECGs and administer the injection. These employees are then added to WhatsApp teams with senior cardiologists who’re in a position to present oversight across the clock.
When an individual with STEMI reaches the spoke inside the timeframe (up to 12 hours of a heart attack) with no issues, they get thrombolysed and are referred to the hubs for additional angiography and angioplasty. This technique is called the pharmaco-invasive technique and is right for low-resource settings equivalent to India the place the affected person demand far outweighs the variety of catheterisation labs.

Pyramid mannequin for thrombolysis choice making, credit score: DMC Ludhiana
| Photograph Credit score:
Swagata Yadavar

Dr Bishav Mohan pointing to the ECG acquired within the Mission AMRIT WhatsApp group.
| Photograph Credit score:
Particular Association
A novel characteristic of ICMR’s mission in Ludhiana was that it was led by Bishav Mohan, who works in who works in Dayanand Medical Faculty, a personal medical faculty and additionally offers the technical help for Mission AMRIT. One other exception of the Ludhiana mission was the inclusion of three personal centres as spokes within the pilot, although personal involvement was discontinued within the precise programme.
“It has taken us a very long time and constant efforts to work on the hesitancy and concern of employees for managing an acute emergency situation like heart attack/STEMI at a secondary health-care degree by way of capability constructing,” mentioned Ashu Gupta, NCD cell, Division of Well being and Household Welfare. “We’re completely happy that regardless of the challenges we’re in a position to run the mission efficiently with none further manpower,” she mentioned.

Dr. Parminder Singh Manghera, Assistant Professor, Cardiology with the nursing employees at GMC Amritsar.
| Photograph Credit score:
Swagata Yadavar
Getting applicable care within the spokes has additionally had an amazing impact in bettering affected person outcomes within the medical faculties. Amritsar’s Authorities Medical Centre (GMC) acts as a hub for six districts round it. Previously 10 months the hub acquired 272 sufferers who had been thrombolysed within the spokes out of which 265 underwent angioplasty at GMC, mentioned Parminder Singh Manghera, Assistant Professor, Cardiology, GMC.
A lot of them may avail the process freed from price underneath Ayushman Bharat-Pradhan Mantri Jan Arogya Yojana (AB-PMJAY) or Punjab authorities’s Mukhyamantri Sehat Bima Yojana that gives Rs. 10 lakh protection to every household.

Operating the programme throughout the state
The success of the mission has depended closely on the efforts of well being officers equivalent to Dr. Gupta who spends a variety of her private time participating with medical doctors within the centres by way of WhatsApp teams, coordinating with them, amassing information and additionally sustaining the provision of tenecteplase throughout 65 centres. Equally, Dr. Bishav Mohan spends hours day by day answering queries, advising the medical doctors on the remedy required and encouraging them to conduct extra thrombolyses by way of a number of WhatsApp teams.
Infrastructural gaps, employees switch and scarcity and excessive affected person numbers exist in lots of of those emergency departments; so protecting these overwhelmed medical groups requires motivational talks, treating nurses as equal companions, use of Punjabi throughout training and technical supplies, awarding greatest performers from the districts on a month-to-month foundation and additionally organising award ceremonies by the well being minister, mentioned Dr Mohan. “As soon as folks begin working, they see that they’re in a position to save lives, this in itself is a morale booster and helps maintain the initiative”,” he mentioned.
STEMI fashions throughout India
After the profitable Tamil Nadu-STEMI pilot that confirmed how a hub-and-spoke mannequin can enhance reperfusion charges and cut back mortality, it was carried out in lots of States together with Tamil Nadu, Goa, Karnataka, and Andhra Pradesh. In most States, spokes are Group Well being Centres (CHCs), sub-divisional hospitals and district hospitals and medical faculties with cath labs are the hubs.
Tamil Nadu has been probably the most profitable State, having handled 72,000 STEMI sufferers and thrombolysed 50,000 over 5 years, with a 67% annual enhance in STEMI sufferers receiving thrombolysis and a 68% enhance in sufferers receiving major angioplasties.
However together with solely the federal government hospitals as hubs is decreasing the effectiveness of the mannequin, mentioned heart specialist Thomas Alexander who together with Ajit Mullasari piloted the TN-STEMI mannequin. “Sufferers lined underneath authorities insurance coverage schemes ought to have entry to the closest reperfusion centre—public or personal—with safeguards to forestall overuse and overcharging,” he mentioned.

Means forward
In Punjab, a 12 months after Mission AMRIT’s implementation, some limitations of the mannequin are obvious–it depends on particular person curiosity and effort. Whereas some spokes like SDH Khanna are doing distinctive work many different spokes have solely carried out a handful of thrombolyses regardless of availability of medicine and skilled employees. Additionally, for the time being there is no such thing as a follow-up as to what occurs to sufferers after they go away the spokes . This follow-up with tertiary care institutes is a part of the subsequent part of the mission, mentioned Dr. Mohan.
Nevertheless, regardless of the challenges, officers say the programme has improved entry. “We’re seeing extra girls from villages above the age of fifty with signs turning up in spoke centres as a result of it’s shut to residence and accessible, we’d have missed this demographic earlier than,” mentioned Dr Mohan.
(Swagata Yadavar is an impartial journalist. swagatayadavar@gmail.com)
(This text is the second of a three-part collection by Nivarana, a digital public well being platform, on the well being system’s response to emergency cardiac care in India. It’s supported by Sunfox Applied sciences)
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